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Usually, the first symptoms of hyperglycaemia develop gradually over a period of hours or days.They include thirst, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, dry mouth, loss of appetite as well as acetone odour of breath.Actrapid dosing is individual and determined in accordance with the needs of the patient.It can be used alone or in combination with intermediate-acting or long-acting insulin before a meal or a snack.For intravenous use, infusion systems with Actrapid at concentrations from 0.05 international unit/ml to 1.0 international unit/ml human insulin in the infusion fluids 0.9% sodium chloride, 5% dextrose and 10% dextrose inclusive 40 mmol/l potassium chloride using polypropylene infusion bags, are stable at room temperature for 24 hours.Although stable over time, a certain amount of insulin will initially be adsorbed to the material of the infusion bag.In type 1 diabetes, untreated hyperglycaemic events eventually lead to diabetic ketoacidosis, which is potentially lethal.Monitoring of blood glucose is necessary during the insulin infusion.


The needle should be kept under the skin for at least 6 seconds to make sure the entire dose is injected.Injection sites should always be rotated within the same region in order to reduce the risk of lipodystrophy.



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