Three years of searching later, the brothers seek the Philosopher's Stone, a mythical relic that allows an alchemist to overcome the Law of Equivalent Exchange.
Even with military allies Colonel Roy Mustang, Lieutenant Riza Hawkeye, and Lieutenant Colonel Maes Hughes on their side, the brothers find themselves caught up in a nationwide conspiracy that leads them not only to the true nature of the elusive Philosopher's Stone, but their country's murky history as well.
In between finding a serial killer and racing against time, Edward and Alphonse must ask themselves if what they are doing will make them human again... [Written by MAL Rewrite]Moments prior to Naruto Uzumaki's birth, a huge demon known as the Kyuubi, the Nine-Tailed Fox, attacked Konohagakure, the Hidden Leaf Village, and wreaked havoc.
It is only by the desperate sacrifice of Edward's right arm that he is able to affix Alphonse's soul to a suit of armor.
Devastated and alone, it is the hope that they would both eventually return to their original bodies that gives Edward the inspiration to obtain metal limbs called "automail" and become a state alchemist, the Fullmetal Alchemist.
To ensure their survival, the remnants of humanity began living within defensive barriers, resulting in one hundred years without a single titan encounter.
However, that fragile calm is soon shattered when a colossal titan manages to breach the supposedly impregnable outer wall, reigniting the fight for survival against the man-eating abominations.
[Written by MAL Rewrite]"In order for something to be obtained, something of equal value must be lost." Alchemy is bound by this Law of Equivalent Exchange—something the young brothers Edward and Alphonse Elric only realize after attempting human transmutation: the one forbidden act of alchemy.
They pay a terrible price for their transgression—Edward loses his left leg, Alphonse his physical body.